Aapptec Vantage Automated Parallel Organic Synthesizer

The Vantage Automated Parallel Organic Synthesizer does it all, no matter if it is carbon-carbon bond formation, nucleophilic displacement, reduction, oxidation or carbohydrate chemistry. It is specially designed for efficient high-throughput solid phase organic synthesis. The Vantage is equipped with an Ares reactor assembly that can cool to –78 °C and heat to 150 °C to facilitate a wide range of organic reactions. Heating and cooling in the Ares reactor is very uniform throughout the reactor assembly, with less than 1.5 °C variation between reactors.

The Ares Reactor assembly allows the performance of organic synthesis not previously possible in a standard open reactor. With complete confidence, low boiling point reagents and solvents, such as DCM, THF and toluene, can be heated above their boiling points without any significant volume loss. The new Teflon™ membrane system independently and completely seals the top and bottom of each reactor and can maintain pressures from 0 to 6 barr. Hence the Vantage can carry out high-pressure reactions that are usually conducted in a sealed tube.

After the library synthesis is completed, the products are automatically cleaved and collected in individual vials, ready for analysis, testing, or evaporation.